Monthly Archives: December 2023

Long-Term Safety of Dupilumab in Patients With Moderate-to-Severe Asthma: TRAVERSE Continuation Study

https://www.jaci-inpractice.org/article/S2213-2198(23)01406-X/fulltext The Journal of Allergy and Clinical Immunology: In Practice, Published: December 30, 2023. DOI: https://doi.org/10.1016/j.jaip.2023.12.043 Jorge F. Maspero, MD, Anju T. Peters, MD, Kenneth R. Chapman, MD, Christian Domingo, MD, John Stewart, MSc, Megan Hardin, MD, Jaman Maroni, MD, … Continue reading

Posted in Uncategorized | Leave a comment

Drug Desensitization Update: Key Concepts and Mechanisms

https://link.springer.com/article/10.1007/s40521-023-00354-5 Current Treatment Options in Allergy, Published: 27 December 2023 Leila A. Alenazy MD MMSc, Sanaalarab Al Enazy PhD & Mariana Castells MD PhD Abstract Purpose of Review Drug allergy is a worldwide healthcare problem, which prevents the use of … Continue reading

Posted in Uncategorized | Leave a comment

Choroidal Mast Cells and Pathophysiology of Age-Related Macular Degeneration

https://www.mdpi.com/2073-4409/13/1/50 Sara Malih, Yong-Seok Song, Christine M. Sorenson and Nader Sheibani Cells 2024, 13(1), 50; https://doi.org/10.3390/cells13010050 / Published: 26 December 2023 (This article belongs to the Special Issue New Insights into Mast Cells Biology) Abstract Age-related macular degeneration (AMD) remains … Continue reading

Posted in Uncategorized | Leave a comment

Modern ideas about the pathogenesis of chronic urticaria. Effective treatments

https://journals.eco-vector.com/2073-4034/article/view/624940 Vol 30, No 9/10 (2023) > Modern ideas about the pathogenesis of chronic urticaria. Effective treatments . DOI: https://doi.org/10.18565/pharmateca.2023.9-10.198-202 Svechnikova E.V., Zhufina S.E. (Polyclinic № 1 of the Administrative Department of the President of the Russian Federation; Russian Biotechnological … Continue reading

Posted in Uncategorized | Leave a comment

Mast Cell: A Mysterious Character in Skin Cancer

https://iv.iiarjournals.org/content/38/1/58 In Vivo January 2024, 38 (1) 58-68; DOI: https://doi.org/10.21873/invivo.13410 SILVIA ALDA, RALUCA AMALIA CEAUSU, PUSA NELA GAJE, MARIUS RAICA and RALUCA MIOARA COSOROABA Abstract Cutaneous malignancies represent a real concern and burden for the healthcare system, not only due … Continue reading

Posted in Uncategorized | Leave a comment

The Burden of Systemic Mastocytosis in Select European Countries: Evidence from the Prism Patient Survey

https://www.valueinhealthjournal.com/article/S1098-3015(23)05705-4/fulltext Value in Health, Volume 26, ISSUE 12, SUPPLEMENT , S475, December 2023. DOI: https://doi.org/10.1016/j.jval.2023.09.2575 R. Mesa, M. Triggiani, J. Hobart, T. Green, D. Powell, C. Gressier-Sayag, W. Baisley, B. Lahue, F. Rueff, W. Schinhofen, N. Hegmann, C. Livideanu, A. … Continue reading

Posted in Uncategorized | Leave a comment

Targeting TRP Channels for Pain, Itch and Neurogenic Inflammation

https://www.mdpi.com/1422-0067/25/1/320 Int. J. Mol. Sci. 2024, 25(1), 320; https://doi.org/10.3390/ijms25010320 / Published: 25 December 2023 Ari-Pekka Koivisto and Arpad Szallasi (Pain Therapy Area, R&D, Orion Pharma, 20360 Turku, Finland; Department of Pathology and Experimental Cancer Research, Semmelweis University, 1083 Budapest, Hungary) … Continue reading

Posted in Uncategorized | Leave a comment

Hereditary Alpha Tryptasemia Presenting as Recurrent Chemotherapy Hypersensitivity Reactions

https://www.annallergy.org/article/S1081-1206(23)01506-5/fulltext Annals of Allergy, Asthma and Immunology, Published: December 25, 2023. DOI: https://doi.org/10.1016/j.anai.2023.12.021 Rose Monahan, MD, Emely Alfaro, MS, CNS, Hansen Ho, PharmD, Iris M. Otani, MD, Lulu R. Tsao, MD A 56-year-old patient with history of high-grade serous ovarian … Continue reading

Posted in Uncategorized | Leave a comment

Capsaicin Pretreatment Increases Mast Cell-Mediated But Not Histamine-Induced Wheal and Erythema Responses: A Proof-of-Concept Study

https://www.researchgate.net/profile/Murat-Tuerk-4/publication/376713024_Capsaicin_Pretreatment_Increases_Mast_Cell-Mediated_But_Not_Histamine-Induced_Wheal_and_Erythema_Responses_A_Proof-of-Concept_Study/links/658439716f6e450f198d4692/Capsaicin-Pretreatment-Increases-Mast-Cell-Mediated-But-Not-Histamine-Induced-Wheal-and-Erythema-Responses-A-Proof-of-Concept-Study.pdf Asthma Allergy Immunol 2023;21:x-x. doi: 10.21911/aai.435 ORCID Murat Türk, İnsu Yılmaz, Sakine Nazik Bahçecioğlu, Gülden Paçacı Çetin, Daniel Elieh-Ali-Komi, Marcus Maurer ABSTRACT Objective: Transient receptor potential (TRP) channels are crucial for the response of many different mediators, including histamine … Continue reading

Posted in Uncategorized | Leave a comment

CREB Is Indispensable to KIT Function in Human Skin Mast Cells-A Positive Feedback Loop between CREB and KIT Orchestrates Skin Mast Cell Fate

https://www.mdpi.com/2073-4409/13/1/42 Gürkan Bal, Jean Schneikert, Zhuoran Li, Kristin Franke, Shiva Raj Tripathi, Torsten Zuberbier and Magda Babina Cells 2024, 13(1), 42; https://doi.org/10.3390/cells13010042 / Published: 24 December 2023 Abstract Skin mast cells (MCs) are critical effector cells in acute allergic reactions, … Continue reading

Posted in Uncategorized | Leave a comment