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Categories
Meta
Monthly Archives: August 2015
Chronic Urticaria is Usually Associated with Fibromyalgia Syndrome
http://www.medicaljournals.se/acta/content/?doi=10.2340%2F00015555-0653&html=1 Claudio Torresani, Salvatore Bellafiore and Giuseppe De Panfilis Section of Dermatology, Department of Surgical Sciences, University of Parma, Parma, Italy Although the pathophysiology of chronic urticaria is not fully understood, it is possible that dysfunctioning of peripheral cutaneous nerve … Continue reading
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Morphologically Occult Systemic Mastocytosis in Bone Marrow: Clinicopathologic Features and an Algorithmic Approach to Diagnosis
http://www.ncbi.nlm.nih.gov/pubmed/26276780 Am J Clin Pathol. 2015 Sep;144(3):493-502. doi: 10.1309/AJCPSGQ71GJQQACL. Reichard KK, Chen D, Pardanani A, McClure RF, Howard MT, Kurtin PJ, Wood AJ, Ketterling RP, King RL, He R, Morice WG, Hanson CA. Abstract OBJECTIVES: Bone marrow (BM) biopsy specimens … Continue reading
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Aberrant expression of CD123 (interleukin-3 receptor-a) on neoplastic mast cells
http://www.ncbi.nlm.nih.gov/pubmed/25640886 http://www.nature.com/leu/journal/v29/n7/full/leu201516a.html Leukemia. 2015 Jul;29(7):1605-8. doi: 10.1038/leu.2015.16. Epub 2015 Feb 2. Pardanani A, Lasho T, Chen D, Kimlinger TK, Finke C, Zblewski D, Patnaik MM, Reichard KK, Rowinsky E, Hanson CA, Brooks C, Tefferi A. The high-affinity receptor for interleukin-3 … Continue reading
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Prognostically relevant breakdown of 123 patients with systemic mastocytosis associated with other myeloid malignancies
http://www.ncbi.nlm.nih.gov/pubmed/19713463 Blood. 2009 Oct 29;114(18):3769-72. doi: 10.1182/blood-2009-05-220145. Epub 2009 Aug 27. Pardanani A, Lim KH, Lasho TL, Finke C, McClure RF, Li CY, Tefferi A. Abstract The prognostic heterogeneity of the World Health Organization category of "systemic mastocytosis with associated … Continue reading
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Glucocorticosteroids: current and future directions
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085866/ Br J Pharmacol. 2011 May; 163(1): 29–43. Peter J Barnes Abstract Glucocorticoids are the most effective anti-inflammatory therapy for asthma yet are relatively ineffective in chronic obstructive pulmonary disease. Glucocorticoids suppress inflammation via several molecular mechanisms. Glucocorticoids suppress the … Continue reading
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Mast cells as regulators of T cell responses
http://journal.frontiersin.org/article/10.3389/fimmu.2015.00394/full Front. Immunol., 07 August 2015 | http://dx.doi.org/10.3389/fimmu.2015.00394 Silvia Bulfone-Paus* and Rajia Bahri Manchester Collaborative Centre for Inflammation Research (MCCIR), Institute of Inflammation and Repair, University of Manchester, Manchester, UK Mast cells (MCs) are recognized to participate in the regulation … Continue reading
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The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production
http://www.ncbi.nlm.nih.gov/pubmed/26283482 J Immunol. 2015 Aug 17. pii: 1401348. [Epub ahead of print] Pundir P, MacDonald CA, Kulka M. Abstract C5a generated during complement activation possesses proinflammatory and immunoregulatory properties critical for the development and modulation of allergic immune responses. In … Continue reading
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The catalytic formation of leukotriene C4: a critical step in inflammatory processes
http://www.ncbi.nlm.nih.gov/pubmed/24974917 Phys Chem Chem Phys. 2014 Aug 14;16(30):16284-9. doi: 10.1039/c4cp01984a. MacDonald CA, Bushnell EA, Gauld JW, Boyd RJ. Abstract Leukotrienes (LT) are a family of drug-like molecules involved in the pathobiology of bronchial asthma and are responsible for smooth muscle … Continue reading
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Pleurocidin, a novel antimicrobial peptide, induces human mast cell activation through the FPRL1 receptor
http://www.ncbi.nlm.nih.gov/pubmed/23839065 Mucosal Immunol. 2014 Jan;7(1):177-87. doi: 10.1038/mi.2013.37. Epub 2013 Jul 10. Pundir P, Catalli A, Leggiadro C, Douglas SE, Kulka M. Abstract Pleurocidins are a novel family of α-helical cationic antimicrobial peptides (CAPs) that are structurally and functionally similar to … Continue reading
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The shorter, the better: A review of the evidence for a shorter contraceptive hormone-free interval
http://www.ncbi.nlm.nih.gov/pubmed/26291185 Eur J Contracept Reprod Health Care. 2015 Aug 20:1-13. [Epub ahead of print] Graziottin A. Abstract Objectives The menstrual cycle is characterised by cyclical fluctuations in oestrogens, progesterone and androgens. Changes in hormone levels in the premenstrual phase with … Continue reading
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