Monthly Archives: September 2010

Demystifying pleomorphic forms in persistence and expression of disease: Are they bacteria, and is peptidoglycan the solution?

http://www.discoverymedicine.com/category/discovery-medicine/no-024/ Discov Med. 2010 Sep;10(52):234-46, Domingue GJ, Professor Emeritus at the Departments of Urology and Microbiology and Immunology, Tulane University School of Medicine, ???consider… Continue reading

Posted in Uncategorized | Leave a comment

Video: Tanezumab helps osteoarthritis, but most trials stopped

http://www.msnbc.msn.com/id/34276015/vp/39428302#39428302 http://www.video-link.tv/09/2010/video-tanezumab-helps-osteoarthritis-but-most-trials-stopped.html Video: Tanezumab helps osteoarthritis, but most trials stopped An experimental arthritis d… Continue reading

Posted in Uncategorized | Leave a comment

Zaditen (Ketotifen), as mast cell blocker, improves sperm quality, chromatin integrity and pregnancy rate after varicocelectomy

Int J Androl. 2010 Sep 27. doi: 10.1111/j.1365-2605, Azadi L, Abbasi H, Deemeh MR, Tavalaee M, Arbabian M, Pilevarian AA, Nasr-Esfahani MH, Isfahan Payame Noor University Isfahan Fertility and Infertility Center Department of Reproduction and Deve… Continue reading

Posted in Uncategorized | Leave a comment

Request for Applications Posted for FDA Orphan Product Development Grants and Orphan Drug Designation Workshop — from NORD

Funding Opportunities Request for Applications Posted for FDA Orphan Product Development Grants A funding opportunity announcement has been posted for FDA Orphan Product Development Grants. These grants support the clinical development of products… Continue reading

Posted in Uncategorized | Leave a comment

Rare Diseases and ("Orphan") drug development — coming events and news from Europe’s Orphanet

Accelerating Therapies for Rare Diseases Workshop Date: 18???20 October 2010 Venue: Rockport, Maryland, USA The Food and Drug Administration (FDA), Center for Drug Evaluation and Research and the National Institutes of Health, Office of Rare Disease… Continue reading

Posted in Uncategorized | Leave a comment

New Scottish study on anaphylactoid reactions to N-acetylcysteine: Mechanisms of N-acetylcysteine Mediated Vascular Adverse Effects

http://clinicaltrials.gov/ct2/show/NCT01209455 (some excerpts follow) Contact: Euan A Sandilands, MRCP BSc +44 131 242 1360 euan.sandilands@luht.scot.nhs.uk Mechanisms of N-acetylcysteine Mediated Vascular Adverse Effects Paracetamol overdose is t… Continue reading

Posted in Uncategorized | Leave a comment

How I treat patients with advanced systemic mastocytosis

[What appear below in green and italics are anonymous editorial remarks submitted to Mastopedia that do not necessarily reflect the views of the Mastopedia website or forums, their owner, managers, nor of other people who subscribe to Mastopedia f… Continue reading

Posted in Uncategorized | Leave a comment

"Exercise-induced Anaphylaxis" – case report from Brigham and Women’s Hospital

[What appear below in green and italics are anonymous editorial remarks submitted to Mastopedia that do not necessarily reflect the views of the Mastopedia website or forums, their owner, managers, nor of other people who subscribe to Mastopedia f… Continue reading

Posted in Uncategorized | Leave a comment

The diagnosis and management of anaphylaxis practice parameter: 2010 Update (free links to full article now available)

http://download.journals.elsevierhealth.com/pdfs/journals/0091-6749/PIIS0091674910010043.pdf http://www.jacionline.org/article/S0091-6749(10)01004-3/fulltext http://www.jacionline.org/article/S0091-6749(10)01004-3/fulltext#appseca15 (???Epinephrine … Continue reading

Posted in Uncategorized | Leave a comment

H3 Receptor Miniseries

http://jpet.aspetjournals.org/content/early/recent Perspectives in Pharmacology: o Lindsay Hough and o Frank L Rice H3 Receptor Miniseries: H3 Receptors and Pain Modulation: Peripheral, Spinal and Brain Interactions J Pharmacol Exp Ther jpet.110.1… Continue reading

Posted in Uncategorized | Leave a comment